Across TCGA cell cohorts, WDR46 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,531 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDR46-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase I promoter, rRNA processing, and Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with WDR46 in more than 17 cancer types. Because this analysis shows association rather than direction, both WDR46-to-partner and partner-to-WDR46 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR46→partner) and Y-score (partner→WDR46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase I promoter →	+0.107	+0.720	.003	.003	2	18
BONE	rRNA processing →	+0.131	+0.819	.003	.001	3	17
LUNG_SCLC	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.146	+0.929	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.137	+0.837	<.001	<.001	3	17
LIVER	Negative regulation of RNA export from nucleus →	+0.115	+0.720	.009	.001	3	16
BLOOD_Myeloma	Maturation of SSU-rRNA →	+0.134	+1.065	.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,531 associations by consensus.

Exploration

WDR46 survival (RNA) · tumor vs normal (RNA) · all WDR46 data types