Across TCGA patient cohorts, WDR45 mutation is significantly associated with the RNA expression of many other genes, with 1,905 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR45-associated genes across cancer lineages are SNRPGP7, ATPAF2, and LINC00904. Each is linked with WDR45 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR45-to-partner and partner-to-WDR45 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR45→partner) and Y-score (partner→WDR45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SNRPGP7 →	+0.405	+4.303	<.001	.009	3	3
UCEC	ATPAF2 →	+0.316	+1.541	<.001	.002	3	3
LIHC	LINC00904 →	+0.110	+4.720	<.001	.005	3	2
LIHC	SSBP3P2 →	+0.063	+4.126	.004	.004	3	2
UCEC	SYPL1P1 →	+0.072	+2.271	<.001	<.001	3	2
LIHC	MLN →	+1.036	+4.000	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,905 associations by consensus.

Exploration

WDR45 survival (RNA) · tumor vs normal (RNA) · all WDR45 data types