Across TCGA cell cohorts, WDR45 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,383 significant associations in total. CNS shows the largest number of these associations.

The most reproducible WDR45-associated GO terms across cancer lineages are Positive regulation of autophagy, Macroautophagy, and Process utilizing autophagic mechanism. Each is linked with WDR45 in more than 15 cancer types. Because this analysis shows association rather than direction, both WDR45-to-partner and partner-to-WDR45 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR45→partner) and Y-score (partner→WDR45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of autophagy →	+0.048	+0.936	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.049	+0.602	<.001	<.001	3	16
BONE	Process utilizing autophagic mechanism →	+0.050	+0.488	<.001	.007	3	15
BONE	Autophagy →	+0.050	+0.488	<.001	.007	3	15
BLOOD_Myeloma	Autophagy of mitochondrion →	+0.073	+1.070	<.001	<.001	3	15
BLOOD_Lymphoma	Regulation of macroautophagy →	+0.061	+1.101	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,383 associations by consensus.

Exploration

WDR45 survival (RNA) · tumor vs normal (RNA) · all WDR45 data types