WDR44

Across TCGA pan-cancer cohorts, WDR44 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated WDR44 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher WDR44 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDR44 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

CCRCC, UCEC, and LUAD are the cancer types where WDR44 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	III,IV	0.463	0.870	.003	18	view →
UCEC	DFS	Median	All	0.962	0.844	.016	12	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	7	view →
HNSC	DFS	Quartile	IV	1.000	0.729	.036	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

WDR44–CCRCC (DFS)

Open the CCRCC breakdown →