WDR44

Across TCGA patient cohorts, WDR44 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,863 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible WDR44-associated proteins across cancer lineages are WDR44_S50, PAIP2B, and PDK1. Each is linked with WDR44 in more than 5 cancer types. Because this analysis shows association rather than direction, both WDR44-to-partner and partner-to-WDR44 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR44 versus WDR44_S50 in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR44→partner) and Y-score (partner→WDR44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WDR44_S50 →	+0.950	+0.622	<.001	<.001	2	6
PDAC	PAIP2B →	-0.629	-0.283	<.001	.001	3	4
BRCA	PDK1 →	-0.651	-0.442	<.001	<.001	3	4
GBM	HPRT1 →	+0.428	+0.320	<.001	<.001	3	4
PDAC	MRPS15 →	-0.319	-0.312	.003	.003	3	4
OV	MRPS9 →	-0.357	-0.610	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,863 associations by consensus.

WDR44 vs WDR44_S50 — BRCA

Explore this scatter interactively →