WDR43

Across TCGA patient cohorts, WDR43 mutation is significantly associated with the RNA expression of many other genes, with 3,445 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR43-associated genes across cancer lineages are RPS26P30, FAM74A7, and NPLP1. Each is linked with WDR43 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR43-to-partner and partner-to-WDR43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS26P30 grouped by WDR43-low versus WDR43-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR43→partner) and Y-score (partner→WDR43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPS26P30 →	+0.088	+4.812	<.001	.006	3	2
BLCA	FAM74A7 →	+0.113	+5.899	<.001	.002	3	2
COAD	NPLP1 →	+0.151	+4.080	<.001	.002	3	2
CESC	GYG2P1 →	+0.020	+4.601	.008	.004	3	2
SKCM	LINC02493 →	+0.020	+4.867	<.001	.005	3	2
SKCM	MIR4516 →	+0.598	+4.595	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,445 associations by consensus.

RPS26P30 by WDR43 expression — CESC

Explore this box plot interactively →