WDR4

Across TCGA patient cohorts, WDR4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,068 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR4-associated proteins across cancer lineages are TBL3, NOL11, and WDR3. Each is linked with WDR4 in more than 7 cancer types. Because this analysis shows association rather than direction, both WDR4-to-partner and partner-to-WDR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR4 versus TBL3 in BRCA, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR4→partner) and Y-score (partner→WDR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TBL3 →	+0.408	+0.665	<.001	<.001	3	8
BRCA	NOL11 →	+0.287	+0.357	<.001	.001	3	7
LSCC	WDR3 →	+0.283	+0.653	<.001	<.001	3	6
LUAD	WDR36 →	+0.271	+0.531	<.001	<.001	3	6
LSCC	XPO5 →	+0.544	+0.649	<.001	<.001	3	6
LSCC	MPHOSPH10 →	+0.311	+0.475	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,068 associations by consensus.

WDR4 vs TBL3 — BRCA

Explore this scatter interactively →