WDR36

Across TCGA pan-cancer cohorts, WDR36 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of WDR36’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where WDR36 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types WDR36 is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

HNSC, BLCA, and THCA are the cancer types where WDR36 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WDR36 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.726	<.001	10	view →
BLCA	All	III,IV	+0.594	.001	9	view →
THCA	Female	All	−0.499	<.001	9	view →
COAD	Male	All	+0.682	<.001	7	view →
KIRP	All	II,III,IV	+0.673	<.001	7	view →
LUAD	Male	All	+0.612	<.001	7	view →
STAD	All	II,III,IV	+0.769	<.001	5	view →
LUSC	Male	All	+0.427	<.001	5	view →
READ	All	III,IV	+1.295	.003	4	view →
CHOL	Male	All	+1.085	.001	4	view →
LIHC	All	All	+0.287	.009	3	view →
ESCA	All	All	+0.682	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

WDR36–HNSC

Open the HNSC breakdown →