WDR35

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, WDR35 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,998 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDR35-associated GO terms across cancer lineages are Intraciliary transport, Protein localization to cilium, and Protein localization to non-motile cilium. Each is linked with WDR35 in more than 16 cancer types. Because this analysis shows association rather than direction, both WDR35-to-partner and partner-to-WDR35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary transport grouped by WDR35-low versus WDR35-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR35→partner) and Y-score (partner→WDR35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHIntraciliary transport →+0.074+1.861<.001<.001317
LUNG_NSCLC_LUSCProtein localization to cilium →+0.087+1.498<.001<.001317
OESOPHAGUSProtein localization to non-motile cilium →+0.134+1.558<.001<.001317
STOMACHIntraciliary anterograde transport →+0.105+1.512<.001<.001316
LUNG_NSCLC_LUSCIntraciliary retrograde transport →+0.101+1.587.003<.001216
BREASTNon-motile cilium assembly →+0.073+0.983<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,998 associations by consensus.

Intraciliary transport by WDR35 expression — STOMACH

Box plot of Intraciliary transport in WDR35-low vs WDR35-high samples in STOMACH.

Explore this box plot interactively →

Exploration