WDR33

Across TCGA cell cohorts, WDR33 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,499 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDR33-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, mRNA 3'-end processing, and Heterochromatin organization. Each is linked with WDR33 in more than 16 cancer types. Because this analysis shows association rather than direction, both WDR33-to-partner and partner-to-WDR33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by WDR33-low versus WDR33-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR33→partner) and Y-score (partner→WDR33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Epigenetic regulation of gene expression →	+0.057	+0.533	<.001	<.001	3	17
LUNG_NSCLC_LUSC	mRNA 3'-end processing →	+0.087	+0.646	<.001	<.001	3	17
STOMACH	Heterochromatin organization →	+0.064	+0.467	<.001	<.001	3	17
STOMACH	Heterochromatin formation →	+0.066	+0.467	<.001	<.001	3	16
STOMACH	Negative regulation of gene expression, epigenetic →	+0.065	+0.491	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Mitotic cell cycle phase transition →	+0.089	+0.707	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,499 associations by consensus.

Epigenetic regulation of gene expression by WDR33 expression — STOMACH

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