WDR33

Across TCGA cell cohorts, WDR33 mutation is significantly associated with the RNA expression of many other genes, with 196 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR33-associated genes across cancer lineages are KRTAP4-4, FZD10, and ATXN3L. Each is linked with WDR33 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR33-to-partner and partner-to-WDR33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP4-4 grouped by WDR33-low versus WDR33-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR33→partner) and Y-score (partner→WDR33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KRTAP4-4 →	+0.024	+4.643	<.001	.005	3	2
BLOOD_Leukemia	FZD10 →	+0.012	+5.149	<.001	.002	3	1
BLOOD_Leukemia	ATXN3L →	+0.316	+3.684	<.001	.004	3	1
BLOOD_Leukemia	MYPN →	+0.027	+3.567	<.001	.003	3	1
BLOOD_Leukemia	CLDN8 →	+0.013	+3.234	<.001	.008	3	1
BLOOD_Leukemia	OR4L1 →	+0.013	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 196 associations by consensus.

KRTAP4-4 by WDR33 expression — BLOOD_Lymphoma

Explore this box plot interactively →