WDR3

Across TCGA patient cohorts, WDR3 protein abundance is significantly associated with the protein abundance of many other proteins, with 30,933 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR3-associated proteins across cancer lineages are RCL1, WDR36, and WDR43. Each is linked with WDR3 in more than 6 cancer types. Because this analysis shows association rather than direction, both WDR3-to-partner and partner-to-WDR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR3 versus RCL1 in LSCC, with a Pearson correlation of 0.78.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR3→partner) and Y-score (partner→WDR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RCL1 →	+0.432	+0.435	<.001	<.001	3	7
LSCC	WDR36 →	+0.493	+0.521	<.001	<.001	3	7
LSCC	WDR43 →	+0.513	+0.470	<.001	<.001	3	7
UCEC	WDR43_S77 →	+0.915	+0.363	<.001	<.001	3	7
OV	WDR75 →	+0.518	+0.438	<.001	<.001	3	7
LSCC	XPO1 →	+0.345	+0.391	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 30,933 associations by consensus.

WDR3 vs RCL1 — LSCC

Explore this scatter interactively →