WDR26

Across TCGA pan-cancer cohorts, WDR26 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of WDR26’s most consistent transcriptional readouts.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where WDR26 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types WDR26 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

CCRCC, COAD, and LSCC are the cancer types where WDR26 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WDR26 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CCRCC	Female	All	+0.175	<.001	10	view →
COAD	Male	II,III,IV	−0.266	<.001	8	view →
LSCC	All	II,III,IV	+0.112	<.001	6	view →
LUAD	All	All	+0.068	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

WDR26–CCRCC

Open the CCRCC breakdown →