WDR20

Across TCGA pan-cancer cohorts, WDR20 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated WDR20 data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher WDR20 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated WDR20 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

PDAC, HNSC, and CCRCC are the cancer types where WDR20 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	II,III,IV	0.739	0.961	.007	26	view →
HNSC	DFS	Median	All	0.264	0.886	.002	18	view →
CCRCC	OS	Median	IV	0.785	0.162	.035	6	view →
LSCC	OS	Quartile	All	0.974	0.844	.033	2	view →
GBM	OS	Median	All	0.952	0.762	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

WDR20–PDAC (OS)

Open the PDAC breakdown →