WDR20

Across TCGA patient cohorts, WDR20 protein abundance is significantly associated with the protein abundance of many other proteins, with 32,653 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WDR20-associated proteins across cancer lineages are ZFYVE21, ARHGAP5, and SETD3. Each is linked with WDR20 in more than 7 cancer types. Because this analysis shows association rather than direction, both WDR20-to-partner and partner-to-WDR20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR20 versus ZFYVE21 in CCRCC, with a Pearson correlation of 0.40.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR20→partner) and Y-score (partner→WDR20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ZFYVE21 →	+0.328	+0.233	<.001	<.001	3	8
COAD	ARHGAP5 →	+0.310	+0.351	<.001	<.001	3	7
LSCC	SETD3 →	+0.394	+0.333	<.001	<.001	3	6
LSCC	ATG2B →	+0.358	+0.330	<.001	<.001	3	6
OV	NUDT14 →	+0.508	+0.297	.002	<.001	3	6
GBM	PACS2 →	+0.284	+0.256	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 32,653 associations by consensus.

WDR20 vs ZFYVE21 — CCRCC

Explore this scatter interactively →