WDR19

Across TCGA pan-cancer cohorts, WDR19 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated WDR19 data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher WDR19 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated WDR19 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCS and UCEC are the cancer types where WDR19 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	All	0.209	0.695	.002	18	view →
UCEC	DFS	Median	All	0.955	0.826	.017	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

WDR19–UCS (OS)

Open the UCS breakdown →