WDR19

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WDR19 protein abundance is significantly associated with the RNA expression of many other genes, with 15,515 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible WDR19-associated genes across cancer lineages are DNAH7, DCDC1, and DRC3. Each is linked with WDR19 in more than 7 cancer types. Because this analysis shows association rather than direction, both WDR19-to-partner and partner-to-WDR19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR19 versus DNAH7 in UCEC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR19→partner) and Y-score (partner→WDR19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECDNAH7 →+1.286+0.466<.001<.00138
UCECDCDC1 →+1.488+0.468<.001<.00138
BRCADRC3 →+1.487+0.560<.001<.00138
UCECEFCAB12 →+1.437+0.448<.001<.00138
BRCACFAP91 →+1.257+0.487<.001<.00138
UCECTSNAXIP1 →+1.248+0.362<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,515 associations by consensus.

WDR19 vs DNAH7 — UCEC

Per-sample scatter of WDR19 vs DNAH7 in UCEC (Pearson r = 0.63).

Explore this scatter interactively →

Exploration