WDR19

Across TCGA cell cohorts, WDR19 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,602 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDR19-associated GO terms across cancer lineages are Intraciliary anterograde transport, Protein localization to ciliary membrane, and Protein localization to cilium. Each is linked with WDR19 in more than 18 cancer types. Because this analysis shows association rather than direction, both WDR19-to-partner and partner-to-WDR19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary anterograde transport grouped by WDR19-low versus WDR19-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR19→partner) and Y-score (partner→WDR19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Intraciliary anterograde transport →	+0.106	+0.870	<.001	<.001	3	19
URINARY_TRACT	Protein localization to ciliary membrane →	+0.139	+1.652	<.001	<.001	3	17
URINARY_TRACT	Protein localization to cilium →	+0.072	+1.461	<.001	<.001	3	17
LUNG_SCLC	Intraciliary transport →	+0.071	+0.817	<.001	<.001	3	17
LUNG_NSCLC_LUAD	Intraciliary retrograde transport →	+0.095	+1.190	<.001	<.001	3	16
LUNG_SCLC	Protein localization to non-motile cilium →	+0.083	+1.019	.002	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,602 associations by consensus.

Intraciliary anterograde transport by WDR19 expression — LUNG_SCLC

Explore this box plot interactively →