WDR18

Across TCGA cell cohorts, WDR18 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR18-associated genes across cancer lineages are MORN5, OR10W1, and SIGLECL1. Each is linked with WDR18 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR18-to-partner and partner-to-WDR18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MORN5 grouped by WDR18-low versus WDR18-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR18→partner) and Y-score (partner→WDR18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MORN5 →	+0.215	+3.855	<.001	.007	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
LARGE_INTESTINE	SIGLECL1 →	+0.022	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MORN5 by WDR18 expression — BLOOD_Leukemia

Explore this box plot interactively →