WDR18

Across TCGA cell cohorts, WDR18 mutation is significantly associated with the mutation status of many other genes, with 2,251 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDR18-associated genes across cancer lineages are MEF2B, KCNK10, and TCFL5. Each is linked with WDR18 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR18-to-partner and partner-to-WDR18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEF2B grouped by WDR18-low versus WDR18-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR18→partner) and Y-score (partner→WDR18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MEF2B →	+4.429	+5.247	.005	.005	1	3
BLOOD_Leukemia	KCNK10 →	+5.430	+4.157	<.001	<.001	1	3
BLOOD_Leukemia	TCFL5 →	+5.167	+4.787	<.001	<.001	1	3
BLOOD_Leukemia	NPRL3 →	+3.108	+3.108	.008	.008	1	3
LARGE_INTESTINE	GCDH →	+4.523	+5.087	.006	.006	1	3
BLOOD_Leukemia	MFN2 →	+3.038	+3.347	.002	.002	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,251 associations by consensus.

MEF2B by WDR18 expression — BLOOD_Lymphoma

Explore this box plot interactively →