WDR17

Across TCGA cell cohorts, WDR17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,571 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WDR17-associated GO terms across cancer lineages are Microtubule organizing center organization, Cardiac conduction, and Positive regulation of cation transmembrane transport. Each is linked with WDR17 in more than 9 cancer types. Because this analysis shows association rather than direction, both WDR17-to-partner and partner-to-WDR17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center organization grouped by WDR17-low versus WDR17-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR17→partner) and Y-score (partner→WDR17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Microtubule organizing center organization →	+0.104	+1.146	<.001	<.001	3	10
OVARY	Cardiac conduction →	-0.138	-1.140	<.001	<.001	3	9
STOMACH	Positive regulation of cation transmembrane transport →	-0.098	-1.198	.001	.001	3	9
SKIN	Regulation of action potential →	-0.110	-0.999	<.001	<.001	3	9
LUNG_SCLC	Centrosome cycle →	+0.109	+1.352	<.001	<.001	3	9
BONE	Cell-cell fusion →	-0.177	-1.115	.003	.007	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,571 associations by consensus.

Microtubule organizing center organization by WDR17 expression — LUNG_SCLC

Explore this box plot interactively →