WDR13

Across TCGA pan-cancer cohorts, WDR13 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated WDR13 data layer compared with 21 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher WDR13 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated WDR13 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, LSCC, and PDAC are the cancer types where WDR13 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.940	0.685	.005	63	view →
LSCC	DFS	Tertile	II,III,IV	0.477	0.897	<.001	56	view →
PDAC	OS	Median	II,III,IV	0.953	0.713	.003	12	view →
COAD	DFS	Median	III,IV	0.895	1.000	.039	6	view →
UCEC	OS	Median	III,IV	0.335	0.904	.045	4	view →
HNSC	DFS	Median	III,IV	1.000	0.939	.043	2	view →
GBM	DFS	Median	All	0.776	0.659	.013	2	view →
LUAD	DFS	Tertile	II,III,IV	0.362	0.691	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

WDR13–CCRCC (OS)

Open the CCRCC breakdown →