Across TCGA pan-cancer cohorts, WDR11-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated WDR11-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher WDR11-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated WDR11-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and BRCA show a favorable association.

KIRP, LIHC, and BRCA are the cancer types where WDR11-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	II,III,IV	0.925	0.710	.001	58	view →
LIHC	OS	Median	All	0.410	0.590	<.001	55	view →
BRCA	DFS	Quartile	III,IV	0.868	0.715	.015	45	view →
LGG	OS	Median	All	0.963	0.827	<.001	43	view →
KIRC	DFS	Median	IV	0.480	0.747	.001	40	view →
KICH	DFS	Median	III,IV	0.373	1.000	.008	34	view →
LUSC	DFS	Tertile	III,IV	0.686	0.279	.001	29	view →
LUAD	OS	Median	All	0.860	0.768	<.001	25	view →
HNSC	OS	Quartile	All	0.836	0.703	.011	24	view →
READ	DFS	Tertile	III,IV	0.520	0.838	.011	23	view →
BLCA	DFS	Quartile	All	0.456	0.272	.002	19	view →
SKCM	DFS	Median	II,III,IV	0.291	0.174	.012	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration

Same gene, other analysis: WDR11-AS1 tumor-vs-normal RNA expression · all WDR11-AS1 data types