WDPCP

Across TCGA patient cohorts, WDPCP protein abundance is significantly associated with the RNA expression of many other genes, with 364 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible WDPCP-associated genes across cancer lineages are INF2, TOP3B, and CENPM. Each is linked with WDPCP in more than 1 cancer types. Because this analysis shows association rather than direction, both WDPCP-to-partner and partner-to-WDPCP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDPCP versus INF2 in GBM, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDPCP→partner) and Y-score (partner→WDPCP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	INF2 →	+1.053	+0.548	.004	.004	2	1
LUAD	TOP3B →	-0.334	-1.634	.008	.004	1	1
LUAD	CENPM →	-1.365	-1.634	.003	.004	1	1
LUAD	RASL10A →	-0.640	-1.634	.003	.004	1	1
LUAD	ETV7 →	-0.970	-1.634	.006	.004	1	1
LUAD	FKBP3 →	-0.765	-1.634	.003	.004	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 364 associations by consensus.

WDPCP vs INF2 — GBM

Explore this scatter interactively →