Across TCGA patient cohorts, WDHD1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,552 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDHD1-associated genes across cancer lineages are PBK, CDC45, and CENPM. Each is linked with WDHD1 in more than 9 cancer types. Because this analysis shows association rather than direction, both WDHD1-to-partner and partner-to-WDHD1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDHD1→partner) and Y-score (partner→WDHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PBK →	+1.416	+0.653	<.001	<.001	3	10
BRCA	CDC45 →	+1.282	+0.625	<.001	<.001	3	10
UCEC	CENPM →	+1.047	+0.397	<.001	<.001	3	9
OV	CDKN3 →	+1.374	+0.577	<.001	<.001	3	9
LUAD	MCM4 →	+0.972	+0.709	<.001	<.001	3	9
UCEC	NEIL3 →	+0.982	+0.657	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,552 associations by consensus.

Exploration

WDHD1 survival (RNA) · tumor vs normal (RNA) · all WDHD1 data types