Across TCGA patient cohorts, WDHD1 mutation is significantly associated with the RNA expression of many other genes, with 2,025 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDHD1-associated genes across cancer lineages are IFI27L1, PSMC3IP, and KIR3DL1. Each is linked with WDHD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDHD1-to-partner and partner-to-WDHD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDHD1→partner) and Y-score (partner→WDHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IFI27L1 →	+0.433	+2.058	.001	<.001	3	3
UCEC	PSMC3IP →	+0.708	+2.606	<.001	<.001	3	3
COAD	KIR3DL1 →	+0.271	+3.915	<.001	.002	3	3
UCEC	GPR3 →	+0.445	+1.523	.006	.008	3	3
UCEC	CIDECP1 →	+0.383	+3.911	<.001	<.001	3	3
UCEC	MTFP1 →	+0.452	+2.807	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,025 associations by consensus.

Exploration

WDHD1 survival (RNA) · tumor vs normal (RNA) · all WDHD1 data types