WDFY3

Across TCGA patient cohorts, WDFY3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,821 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible WDFY3-associated proteins across cancer lineages are RPL5, SEPTIN11, and DDX21_S121. Each is linked with WDFY3 in more than 4 cancer types. Because this analysis shows association rather than direction, both WDFY3-to-partner and partner-to-WDFY3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDFY3 versus RPL5 in GBM, with a Pearson correlation of -0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDFY3→partner) and Y-score (partner→WDFY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL5 →	-0.248	-0.323	<.001	<.001	3	5
BRCA	SEPTIN11 →	+0.280	+0.705	.002	<.001	3	5
BRCA	DDX21_S121 →	-0.850	-0.630	<.001	<.001	3	5
LUAD	EIF4B →	-0.273	-0.447	<.001	<.001	3	5
PDAC	ENOPH1 →	+0.422	+0.336	<.001	<.001	3	5
LUAD	H1-4_T18 →	-1.301	-0.338	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,821 associations by consensus.

WDFY3 vs RPL5 — GBM

Explore this scatter interactively →