WDFY3

Across TCGA patient cohorts, WDFY3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,854 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDFY3-associated genes across cancer lineages are SEC31A, WDFY3-AS2, and KIF24. Each is linked with WDFY3 in more than 4 cancer types. Because this analysis shows association rather than direction, both WDFY3-to-partner and partner-to-WDFY3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDFY3 versus SEC31A in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDFY3→partner) and Y-score (partner→WDFY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SEC31A →	+0.684	+0.284	<.001	<.001	3	5
UCEC	WDFY3-AS2 →	+0.479	+0.149	<.001	<.001	3	5
UCEC	KIF24 →	-0.633	-0.180	.001	.001	3	5
LSCC	LINC02516 →	+0.540	+0.277	.001	<.001	3	5
OV	RPS18 →	-0.627	-0.210	.009	.001	3	5
OV	COLEC12 →	+0.910	+0.195	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,854 associations by consensus.

WDFY3 vs SEC31A — OV

Explore this scatter interactively →