WDFY3-AS1

Across TCGA pan-cancer cohorts, WDFY3-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated WDFY3-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher WDFY3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDFY3-AS1 expression acts as an unfavorable survival marker, although some lineages such as LAML and BRCA show a favorable association.

KICH, OV, and READ are the cancer types where WDFY3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	II,III,IV	0.447	0.879	<.001	109	view →
OV	DFS	Tertile	All	0.099	0.177	.002	72	view →
READ	OS	Tertile	IV	0.289	0.899	<.001	72	view →
ACC	OS	Quartile	All	0.256	0.691	<.001	67	view →
SKCM	OS	Tertile	All	0.607	0.801	<.001	66	view →
MESO	OS	Tertile	II,III,IV	0.147	0.625	.001	60	view →
STAD	DFS	Median	III,IV	0.496	0.659	.005	55	view →
LAML	DFS	Median	All	0.498	0.269	.005	38	view →
TGCT	OS	Tertile	II,III,IV	0.670	1.000	.005	36	view →
BRCA	DFS	Tertile	III,IV	0.726	0.449	.010	24	view →
ESCA	OS	Median	IV	0.222	0.698	.006	18	view →
KIRP	DFS	Tertile	III,IV	0.475	0.769	.024	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

WDFY3-AS1–KICH (DFS)

Open the KICH breakdown →