WDFY2

Across TCGA patient cohorts, WDFY2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,083 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDFY2-associated proteins across cancer lineages are GTF2F2, KPNA3, and UAP1. Each is linked with WDFY2 in more than 4 cancer types. Because this analysis shows association rather than direction, both WDFY2-to-partner and partner-to-WDFY2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDFY2 versus GTF2F2 in GBM, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDFY2→partner) and Y-score (partner→WDFY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GTF2F2 →	+0.323	+0.379	<.001	<.001	3	5
BRCA	KPNA3 →	+0.309	+0.424	.005	.003	3	5
GBM	UAP1 →	-0.711	-0.563	<.001	<.001	3	4
GBM	NUDT15 →	+0.379	+0.426	<.001	<.001	3	4
LSCC	BLNK_S141 →	-0.817	-0.858	.005	.003	3	4
LSCC	DNAJC1 →	-0.567	-0.789	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,083 associations by consensus.

WDFY2 vs GTF2F2 — GBM

Explore this scatter interactively →