WDFY2

Across TCGA patient cohorts, WDFY2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,491 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDFY2-associated genes across cancer lineages are CCDC34, S100A12, and CEP70. Each is linked with WDFY2 in more than 3 cancer types. Because this analysis shows association rather than direction, both WDFY2-to-partner and partner-to-WDFY2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDFY2 versus CCDC34 in BRCA, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDFY2→partner) and Y-score (partner→WDFY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CCDC34 →	-0.781	-0.306	<.001	.001	3	4
HNSC	S100A12 →	+1.395	+0.166	<.001	.009	3	4
HNSC	CEP70 →	-0.592	-0.220	.001	<.001	3	3
LUAD	C19orf48 →	-0.674	-0.245	<.001	<.001	3	3
LSCC	FLRT2 →	+0.976	+0.299	<.001	<.001	3	3
CCRCC	SP5 →	-0.669	-0.262	.003	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,491 associations by consensus.

WDFY2 vs CCDC34 — BRCA

Explore this scatter interactively →