WDFY2

Across TCGA cell cohorts, WDFY2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,846 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDFY2-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Microtubule nucleation, and Centrosome duplication. Each is linked with WDFY2 in more than 14 cancer types. Because this analysis shows association rather than direction, both WDFY2-to-partner and partner-to-WDFY2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by WDFY2-low versus WDFY2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDFY2→partner) and Y-score (partner→WDFY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Viral translational termination-reinitiation →	+0.089	+1.081	.001	.003	3	15
LARGE_INTESTINE	Microtubule nucleation →	+0.130	+1.195	<.001	<.001	3	15
BONE	Centrosome duplication →	+0.134	+1.064	<.001	<.001	3	13
BONE	Microtubule polymerization or depolymerization →	+0.125	+1.083	<.001	.001	3	13
OESOPHAGUS	mRNA splice site recognition →	+0.149	+1.124	<.001	<.001	3	13
BONE	Positive regulation of DNA metabolic process →	+0.084	+1.033	.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,846 associations by consensus.

Viral translational termination-reinitiation by WDFY2 expression — OESOPHAGUS

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