WDFY1

Across TCGA patient cohorts, WDFY1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,898 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible WDFY1-associated proteins across cancer lineages are RPL6, SP100, and OMA1. Each is linked with WDFY1 in more than 3 cancer types. Because this analysis shows association rather than direction, both WDFY1-to-partner and partner-to-WDFY1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDFY1 versus RPL6 in BRCA, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDFY1→partner) and Y-score (partner→WDFY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL6 →	-0.374	-0.557	.001	<.001	3	4
OV	SP100 →	+0.340	+0.658	.005	<.001	3	4
PDAC	OMA1 →	-0.490	-0.357	.002	<.001	3	4
PDAC	SERPINB8 →	+0.543	+0.420	<.001	<.001	3	4
CCRCC	PPM1F →	+0.251	+0.285	.001	.007	3	3
CCRCC	PXN →	+0.236	+0.370	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,898 associations by consensus.

WDFY1 vs RPL6 — BRCA

Explore this scatter interactively →