WDFY1

Across TCGA patient cohorts, WDFY1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,730 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDFY1-associated genes across cancer lineages are SERPING1, IFFO1, and AEBP1. Each is linked with WDFY1 in more than 7 cancer types. Because this analysis shows association rather than direction, both WDFY1-to-partner and partner-to-WDFY1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDFY1 versus SERPING1 in OV, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDFY1→partner) and Y-score (partner→WDFY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SERPING1 →	+1.251	+0.281	.001	<.001	3	8
BRCA	IFFO1 →	+0.863	+0.294	<.001	<.001	3	7
OV	AEBP1 →	+1.579	+0.267	.001	.002	3	7
OV	PRRX1 →	+1.345	+0.217	<.001	<.001	3	7
BRCA	CNRIP1 →	+0.760	+0.185	<.001	<.001	3	7
OV	PLXNC1 →	+0.823	+0.211	.001	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,730 associations by consensus.

WDFY1 vs SERPING1 — OV

Explore this scatter interactively →