WDFY1

Across TCGA patient cohorts, WDFY1 mutation is significantly associated with the RNA expression of many other genes, with 792 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDFY1-associated genes across cancer lineages are MIR550A2, RN7SKP154, and RNA5SP235. Each is linked with WDFY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDFY1-to-partner and partner-to-WDFY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR550A2 grouped by WDFY1-low versus WDFY1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDFY1→partner) and Y-score (partner→WDFY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR550A2 →	+0.417	+5.141	<.001	.001	3	2
HNSC	RN7SKP154 →	+0.262	+5.224	<.001	.001	3	2
UCEC	RNA5SP235 →	+0.200	+2.985	<.001	.006	3	2
UCEC	RN7SKP232 →	+0.108	+2.285	.001	.005	3	2
UCEC	RNU6-1140P →	+0.273	+1.856	.001	.007	3	2
UCEC	LINC02438 →	+0.842	+4.024	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 792 associations by consensus.

MIR550A2 by WDFY1 expression — HNSC

Explore this box plot interactively →