WDFY1

Across TCGA cell cohorts, WDFY1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,178 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WDFY1-associated GO terms across cancer lineages are Establishment of protein localization to vacuole, Vacuolar transport, and Cytosolic transport. Each is linked with WDFY1 in more than 10 cancer types. Because this analysis shows association rather than direction, both WDFY1-to-partner and partner-to-WDFY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to vacuole grouped by WDFY1-low versus WDFY1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDFY1→partner) and Y-score (partner→WDFY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Establishment of protein localization to vacuole →	+0.063	+0.691	<.001	<.001	3	11
URINARY_TRACT	Vacuolar transport →	+0.057	+0.650	<.001	<.001	3	11
SKIN	Cytosolic transport →	+0.064	+1.033	<.001	<.001	3	10
LARGE_INTESTINE	Retrograde transport, endosome to Golgi →	+0.062	+1.032	<.001	<.001	3	10
OVARY	Regulation of cell-substrate junction organization →	+0.082	+0.892	.002	.001	3	10
CNS	Regulation of cell-matrix adhesion →	+0.094	+0.597	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,178 associations by consensus.

Establishment of protein localization to vacuole by WDFY1 expression — BREAST

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