WDCP

Across TCGA pan-cancer cohorts, WDCP mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated WDCP data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher WDCP mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated WDCP expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, HNSC, and PDAC are the cancer types where WDCP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.870	0.468	.001	43	view →
HNSC	OS	Quartile	All	0.176	0.964	.038	16	view →
PDAC	DFS	Tertile	All	0.508	0.205	.011	15	view →
LSCC	OS	Quartile	II,III,IV	0.945	0.540	.005	9	view →
UCEC	OS	Median	All	0.852	0.968	.026	4	view →
CCRCC	DFS	Median	All	0.840	0.457	.025	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

WDCP–LUAD (OS)

Open the LUAD breakdown →