WBP1L

Across TCGA pan-cancer cohorts, WBP1L mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated WBP1L data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher WBP1L mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated WBP1L expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

HNSC and GBM are the cancer types where WBP1L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.395	0.804	.045	8	view →
GBM	DFS	Quartile	All	0.548	0.194	.004	8	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

WBP1L–HNSC (DFS)

Open the HNSC breakdown →