WBP11P1

Across TCGA patient cohorts, WBP11P1 mutation is significantly associated with the RNA expression of many other genes, with 3,781 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WBP11P1-associated genes across cancer lineages are SAMD9, RNU6-752P, and SFTPD. Each is linked with WBP11P1 in more than 2 cancer types. Because this analysis shows association rather than direction, both WBP11P1-to-partner and partner-to-WBP11P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAMD9 grouped by WBP11P1-low versus WBP11P1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP11P1→partner) and Y-score (partner→WBP11P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SAMD9 →	-0.777	-3.087	.001	<.001	3	3
SKCM	RNU6-752P →	+0.120	+3.419	<.001	<.001	3	3
UCEC	SFTPD →	-0.734	-3.000	.002	<.001	3	3
UCEC	MIR3661 →	+0.600	+1.578	<.001	.003	3	3
BRCA	RNU6-502P →	+0.535	+5.347	<.001	.006	3	2
BRCA	ARF4P3 →	+0.087	+4.995	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,781 associations by consensus.

SAMD9 by WBP11P1 expression — SKCM

Explore this box plot interactively →