WBP1

Across TCGA patient cohorts, WBP1 mutation is significantly associated with the RNA expression of many other genes, with 647 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WBP1-associated genes across cancer lineages are RN7SKP286, LINC02133, and OR7E149P. Each is linked with WBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both WBP1-to-partner and partner-to-WBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP286 grouped by WBP1-low versus WBP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WBP1→partner) and Y-score (partner→WBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP286 →	+0.050	+4.153	<.001	.005	3	2
UCEC	LINC02133 →	+0.064	+2.013	.003	.005	3	2
UCEC	OR7E149P →	+0.051	+2.496	<.001	.003	3	2
CESC	RNU4-31P →	+0.236	+3.874	<.001	.006	3	2
COAD	LINC01995 →	+0.198	+4.418	<.001	.008	3	2
COAD	RN7SL25P →	+0.525	+4.484	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 647 associations by consensus.

RN7SKP286 by WBP1 expression — UCEC

Explore this box plot interactively →