WASL

Across TCGA patient cohorts, WASL protein abundance is significantly associated with the RNA expression of many other genes, with 13,561 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible WASL-associated genes across cancer lineages are WASL-DT, FPR2, and FCRL5. Each is linked with WASL in more than 7 cancer types. Because this analysis shows association rather than direction, both WASL-to-partner and partner-to-WASL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WASL versus WASL-DT in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASL→partner) and Y-score (partner→WASL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WASL-DT →	+0.653	+0.236	<.001	<.001	3	8
PDAC	FPR2 →	-1.156	-0.386	<.001	<.001	3	8
HNSC	FCRL5 →	-1.406	-0.274	<.001	<.001	3	7
LSCC	CEACAM3 →	-0.769	-0.251	<.001	<.001	3	7
LSCC	TMEM248 →	+0.460	+0.256	<.001	<.001	3	6
HNSC	POU2AF1 →	-1.208	-0.264	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,561 associations by consensus.

WASL vs WASL-DT — BRCA

Explore this scatter interactively →