WASL

Across TCGA patient cohorts, WASL mutation is significantly associated with the RNA expression of many other genes, with 1,119 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WASL-associated genes across cancer lineages are LAMTOR3P1, MTND1P19, and RNA5SP341. Each is linked with WASL in more than 2 cancer types. Because this analysis shows association rather than direction, both WASL-to-partner and partner-to-WASL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LAMTOR3P1 grouped by WASL-low versus WASL-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASL→partner) and Y-score (partner→WASL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LAMTOR3P1 →	+0.281	+3.821	<.001	.007	3	3
KIRC	MTND1P19 →	+0.309	+5.081	<.001	.004	3	2
KIRC	RNA5SP341 →	+0.331	+5.901	<.001	<.001	3	2
KIRC	MIR3664 →	+0.517	+4.376	<.001	.007	3	2
COAD	KCTD9 →	+0.907	+3.375	<.001	.005	3	2
UCEC	CORO1C →	+0.453	+1.736	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,119 associations by consensus.

LAMTOR3P1 by WASL expression — LUAD

Explore this box plot interactively →