WASL

Across TCGA cell cohorts, WASL mutation is significantly associated with the drug of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WASL-associated genes across cancer lineages are OF-1, GSK429286A, and CX-5461. Each is linked with WASL in more than 1 cancer types. Because this analysis shows association rather than direction, both WASL-to-partner and partner-to-WASL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OF-1 grouped by WASL-low versus WASL-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASL→partner) and Y-score (partner→WASL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OF-1 →	+0.300	+2.646	.038	.047	3	1
LARGE_INTESTINE	GSK429286A →	+0.375	+2.652	.015	.045	3	1
LARGE_INTESTINE	CX-5461 →	+0.648	+2.652	.028	.045	3	1
LARGE_INTESTINE	Torin 2 →	+0.537	+2.655	.047	.044	3	1
LARGE_INTESTINE	GSK690693 →	+0.894	+2.652	<.001	.045	2	1
LARGE_INTESTINE	Dacarbazine →	+0.287	+2.777	.040	.038	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OF-1 by WASL expression — LARGE_INTESTINE

Explore this box plot interactively →