WASL-DT

Across TCGA pan-cancer cohorts, WASL-DT RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated WASL-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher WASL-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated WASL-DT expression acts as an unfavorable survival marker, although some lineages such as KIRC and OV show a favorable association.

KIRC, OV, and BRCA are the cancer types where WASL-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.704	0.557	<.001	87	view →
OV	DFS	Tertile	III,IV	0.609	0.455	<.001	76	view →
BRCA	OS	Tertile	All	0.978	0.938	.001	59	view →
UCS	DFS	Median	II,III,IV	0.532	0.189	.006	32	view →
SARC	OS	Tertile	All	0.825	0.584	.002	25	view →
MESO	OS	Quartile	All	0.702	0.329	<.001	24	view →
READ	OS	Quartile	II,III,IV	0.918	0.311	.013	19	view →
COAD	DFS	Quartile	IV	0.682	0.185	.001	15	view →
LIHC	DFS	Median	All	0.161	0.404	<.001	15	view →
HNSC	OS	Tertile	All	0.826	0.594	.006	14	view →
UVM	OS	Median	III,IV	0.638	1.000	.016	13	view →
CESC	DFS	Tertile	IV	0.212	0.688	.009	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

WASL-DT–KIRC (OS)

Open the KIRC breakdown →