WASHC5

Across TCGA pan-cancer cohorts, WASHC5 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated WASHC5 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher WASHC5 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated WASHC5 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

PDAC, LUAD, and CCRCC are the cancer types where WASHC5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.242	0.566	.001	40	view →
LUAD	DFS	Quartile	III,IV	1.000	0.200	.008	19	view →
CCRCC	DFS	Tertile	III,IV	0.887	0.198	.024	5	view →
OV	DFS	Median	All	1.000	0.860	.028	4	view →
UCEC	OS	Tertile	All	0.950	0.807	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

WASHC5–PDAC (DFS)

Open the PDAC breakdown →