WASHC5

Across TCGA cell cohorts, WASHC5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,894 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WASHC5-associated GO terms across cancer lineages are Positive regulation of sister chromatid cohesion, Synaptic vesicle lumen acidification, and Meiotic spindle assembly. Each is linked with WASHC5 in more than 10 cancer types. Because this analysis shows association rather than direction, both WASHC5-to-partner and partner-to-WASHC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of sister chromatid cohesion grouped by WASHC5-low versus WASHC5-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WASHC5→partner) and Y-score (partner→WASHC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of sister chromatid cohesion →	+0.105	+0.452	<.001	.008	3	11
SOFT_TISSUE	Synaptic vesicle lumen acidification →	+0.190	+0.720	<.001	<.001	3	11
LUNG_SCLC	Meiotic spindle assembly →	+0.131	+0.870	.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome →	+0.112	+0.925	.001	<.001	3	10
LUNG_SCLC	Vacuolar transport →	+0.063	+0.886	<.001	.001	2	10
UPPER_AERODIGESTIVE_TRACT	Blastocyst growth →	+0.140	+0.669	<.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,894 associations by consensus.

Positive regulation of sister chromatid cohesion by WASHC5 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →