WASHC5

Across TCGA cell cohorts, WASHC5 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WASHC5-associated genes across cancer lineages are IGFL3, TPPP2, and PAX4. Each is linked with WASHC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both WASHC5-to-partner and partner-to-WASHC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGFL3 grouped by WASHC5-low versus WASHC5-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASHC5→partner) and Y-score (partner→WASHC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	IGFL3 →	+0.504	+3.688	<.001	.007	3	2
LUNG_SCLC	TPPP2 →	+0.067	+3.898	<.001	.005	3	2
URINARY_TRACT	PAX4 →	+0.024	+4.584	<.001	.002	3	1
URINARY_TRACT	OR2D3 →	+0.015	+4.087	<.001	.009	3	1
SKIN	GPR88 →	+0.051	+4.000	<.001	.004	3	1
SKIN	TMEM239 →	+0.101	+3.920	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

IGFL3 by WASHC5 expression — STOMACH

Explore this box plot interactively →