WASHC5-AS1

Across TCGA pan-cancer cohorts, WASHC5-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated WASHC5-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher WASHC5-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated WASHC5-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and SKCM show a favorable association.

UVM, BRCA, and UCEC are the cancer types where WASHC5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	III,IV	0.324	0.794	<.001	73	view →
BRCA	DFS	Quartile	III,IV	0.941	0.794	.005	28	view →
UCEC	DFS	Tertile	All	0.785	0.890	.005	26	view →
KIRP	DFS	Quartile	All	0.526	0.853	<.001	24	view →
PRAD	DFS	Median	All	0.734	0.827	.001	22	view →
STAD	DFS	Median	III,IV	0.389	0.572	.002	17	view →
KICH	DFS	Quartile	All	0.770	1.000	.026	15	view →
SKCM	OS	Median	III,IV	0.484	0.308	.004	13	view →
THCA	DFS	Tertile	II,III,IV	0.884	0.972	.017	13	view →
MESO	OS	Tertile	IV	0.238	0.855	.020	9	view →
READ	DFS	Median	IV	0.410	0.730	.031	8	view →
DLBC	DFS	Tertile	All	0.626	0.944	.016	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

WASHC5-AS1–UVM (DFS)

Open the UVM breakdown →