WASHC4

Across TCGA patient cohorts, WASHC4 mutation is significantly associated with the RNA expression of many other genes, with 4,329 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WASHC4-associated genes across cancer lineages are MIR6894, RNU6-1213P, and OR1D4. Each is linked with WASHC4 in more than 2 cancer types. Because this analysis shows association rather than direction, both WASHC4-to-partner and partner-to-WASHC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6894 grouped by WASHC4-low versus WASHC4-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASHC4→partner) and Y-score (partner→WASHC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6894 →	+0.611	+5.506	<.001	.005	3	3
UCEC	RNU6-1213P →	+0.175	+3.332	<.001	<.001	3	3
BRCA	OR1D4 →	+0.036	+5.800	.006	.003	3	2
BLCA	BRI3P2 →	+0.068	+3.177	.001	.008	3	2
BLCA	SNX19P1 →	+0.027	+3.177	<.001	.008	3	2
UCEC	FAM177A1 →	+0.308	+2.617	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,329 associations by consensus.

MIR6894 by WASHC4 expression — BRCA

Explore this box plot interactively →