WASHC2A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WASHC2A protein abundance is significantly associated with the RNA expression of many other genes, with 9,364 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WASHC2A-associated genes across cancer lineages are LY86, BTK, and SFMBT2. Each is linked with WASHC2A in more than 5 cancer types. Because this analysis shows association rather than direction, both WASHC2A-to-partner and partner-to-WASHC2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WASHC2A versus LY86 in LSCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WASHC2A→partner) and Y-score (partner→WASHC2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCLY86 →+0.829+0.204<.001<.00136
GBMBTK →+0.827+0.256<.001.00235
UCECSFMBT2 →+0.767+0.181.001.00835
UCECATP8B4 →+0.655+0.202.001<.00125
UCECARHGEF6 →+0.746+0.188.001.00734
LSCCDOCK10 →+0.651+0.216<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,364 associations by consensus.

WASHC2A vs LY86 — LSCC

Per-sample scatter of WASHC2A vs LY86 in LSCC (Pearson r = 0.36).

Explore this scatter interactively →

Exploration